ACE I/D polymorphism and recurrent first trimester pregnancy loss: interaction with SERPINE1 4G/5G and F13 Val34Leu polymorphisms
نویسندگان
چکیده
منابع مشابه
ACE and MTHFR gene polymorphisms in unexplained recurrent pregnancy loss.
AIM To assess the association between polymorphisms in angiotensin converting enzyme and methylene tetrahydrofolate reductase genes and recurrent pregnancy loss by a case-control study in South Indian women. METHODS DNA was extracted from peripheral blood leukocytes of 104 women with Recurrent Pregnancy Loss (RPL) and 120 controls. Genotyping of ACE Insertion Deletion and MTHFR C677T polymorp...
متن کاملUnexplained first trimester recurrent pregnancy loss and low venous reserves.
BACKGROUND More than half of recurrent pregnancy loss (RPL) remains unexplained. We hypothesized that women with a history of unexplained RPL (URPL) have low venous reserve. METHODS Case-control study in 12 women with a history of URPL, 11 healthy nulliparous controls and 12 primiparous controls with a history of uncomplicated pregnancy. To quantify venous reserve, we measured plasma volume (...
متن کاملPrevalence of hypothyroidism in recurrent pregnancy loss in first trimester.
AIM To determine the frequency of hypothyroidism in women with recurrent pregnancy loss in first trimester in the Indian population. SETTINGS AND DESIGN The study included 163 non-pregnant women with recurrent pregnancy loss in a gestational age up to <or=12 weeks verified by a pregnancy test or ultrasonography, and a total of 170 age matched women with at least one successful pregnancy and n...
متن کاملFirst and Second Trimester Pregnancy Loss
Pathologic exa mination o f t he p roducts o f em bryos a nd fetuses, both from spontaneous abortions (SAbs) and terminations of pregnancy, has become increasingly important. While s uch exa mination wa s o nce p erformed p rimarily for t he p urpose o f f urthering s cientiἀc un derstanding o f prenatal human development, the practical medical applications of this knowledge have become clear a...
متن کاملP-193: The Association of Apolipoprotien E Polymorphisms with Recurrent Pregnancy Loss
Background: The role of apolipoprotien E polymorphisms do not diagnostic correctly in recurrent pregnancy loss etiology but Apo E has been shown to play an important role in lipid metabolism in pregnancy. We evaluated these polymorphisms in Iranian women with unexplained recurrent pregnancy loss. Materials and Methods: 5 ml Blood were sampling from 81 women with a history of two or more consecu...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2008
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.2008.07058.x